Nasal Inverted Papilloma
Inverted papilloma of nasal cavity and paranasal sinuses is a kind of mucosal epithelial-derived tumor occurring in the lateral wall of nasal cavity and nasal sinus, which accounts for 0.5-4% of nasal cavity tumor.
Tumorigenesis is associated with inflammatory stimulation, papillomavirus or Epstein-Barr virus infection and biochemistry of phosphorous epithelial cells in mucosal glands, which is a transformed or endogenetic tumor. The pathological features were overproliferation of surface epithelium, papillary hyperplasia to matrix, squamous epithelium, transitional epithelium and ciliated columnar epithelium. The epithelium turned inward to form solid cell nests or cell mass, but the basement membrane was intact, and the heterogeneity of tumor cells was not serious. Although benign in the structure of tumor tissue, but has a strong growth force, can occur as a multicenter, easy to damage the surrounding tissue and bone, expand to adjacent organs, after resectionIt is easy to relapse and have a tendency to change. Therefore, it has a certain limit for the qualitative diagnosis of the malignant tumor, the precancerous state or the potential malignant tumor.CT, but it has a great effect on determining the location of the disease, the range of involvement and helping to make the appropriate surgical procedure. The NIP clinical staging standard can objectively evaluate the effect of different surgical methods on the treatment of NIP, and is beneficial to the application of nasal endoscopy in the treatment of NIP. There have been many authors on the staging of NIP. At present, most of the literature reports on the use of Krouse staging.The tumor was confined to an anatomic site of the nasal cavity, stage II: the tumor was confined to the inner wall of the sinusoidal oronasal complex, ethmoid sinus and / or superior collar sinus. Chuan stage: recurrence or involvement of the whole group of sinus with bone destruction; stage IV: lesion invades the structure or malignant change of the nasal cavity and paranasal sinus.